Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 9/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL6528425 | 0.90 | ALDH1A1 (0.43) | AOC3KDM4EADRA2AADRA2CLMNA | |
| SCHEMBL7372396 | 0.80 | AOC3 (0.40) | AOC3KDM4ELMNAALDH1A1SLC6A2 | |
| Hydrochloric Acid SCHEMBL6287950 | 0.78 | AOC3 (0.39) | AOC3KDM4ELMNAALDH1A1SLC6A2 | |
| SCHEMBL2721666 | 0.76 | ALDH1A1 (0.42) | AOC3ADRA2ALMNAALDH1A1ALOX5 | |
| SCHEMBL1983878 | 0.76 | ALDH1A1 (0.42) | AOC3ADRA2ALMNAALDH1A1ALOX5 | |
| SCHEMBL5076555 | 0.75 | ALDH1A1 (0.46) | AOC3KDM4EADRA2AADRA2CLMNA | |
| SCHEMBL104211 | 0.75 | POLB (0.44) | AOC3KDM4EADRA2AADRA2CLMNA | |
| SCHEMBL27578487 | 0.74 | AOC3 (0.47) | AOC3ALDH1A1ALOX5SLC6A2SLC6A4 | |
| SCHEMBL12157017 | 0.73 | SLC6A2 (0.48) | AOC3KDM4ELMNAALDH1A1SLC6A2 | |
| SCHEMBL28313320 | 0.73 | ALDH1A1 (0.52) | AOC3KDM4EADRA2AADRA2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7455697-B2 | (3,5-diaminophenyl)(2,4-dihydroxyphenyl)methanone and the acid adducts thereof, method for their preparation and use of these compounds for dyeing fibers | WELLA AG (DE) | 2008-11-25 | — | — | US | disclosed |
| US-20070180629-A1 | (3,5-Diaminophenyl)(2,4-dihydroxyphenyl)methanone and the acid adducts thereof, method for their preparation and use of these compounds for dyeing fibers | Wella GmbH (DE) | 2007-08-09 | — | — | US | disclosed |
| US-6180818-B1 | COMPOUND PROVIDING IMPROVED STORAGE STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 2001-01-30 | — | — | US | disclosed |
| US-5086052-A | Antiarthritic, antiallergens, antiinflammatory agents; also for asthma and psoriasis | ABBOTT LABORATORIES (US) | 1992-02-04 | — | — | US | disclosed |
| US-4970210-A | ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1990-11-13 | — | — | US | disclosed |
| EP-0299449-A2 | Pyridazinone, triazinone and oxapyridazinone lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1989-01-18 | — | — | EP | disclosed |
| US-4260770-A | Naphtholactam dyes | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070180629-A1 | (3,5-Diaminophenyl)(2,4-dihydroxyphenyl)methanone and the acid adducts thereof, method for their preparation and use of these compounds for dyeing fibers | GRHPR, MB, COX5B | AOC3 285/4885KDM4E 2256/4885ADRA2A 310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.