Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL946382 | 0.80 | TDP1 (0.56) | GAAALDH1A1TDP1CTSDTSHR | |
| SCHEMBL7213152 | 0.80 | TDP1 (0.56) | GAAALDH1A1TDP1CTSDTSHR | |
| SCHEMBL10901615 | 0.77 | TDP1 (0.56) | GAAALDH1A1TDP1CTSDTSHR | |
| SCHEMBL9297146 | 0.73 | GAA (0.50) | GAAALDH1A1TDP1CTSDTSHR | |
| SCHEMBL27405771 | 0.72 | GAA (0.55) | GAAALDH1A1TDP1CTSDTSHR | |
| SCHEMBL1339975 | 0.72 | GAA (0.55) | GAAALDH1A1TDP1CTSDTSHR | |
| SCHEMBL13345205 | 0.71 | HSD17B10 (0.48) | GAAALDH1A1TDP1CTSDCYP3A4 | |
| SCHEMBL18899276 | 0.71 | ALDH1A1 (0.48) | GAAALDH1A1TDP1CTSDTSHR | |
| SCHEMBL7748287 | 0.71 | GAA (0.61) | GAAALDH1A1CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL7748103 | 0.71 | HSD17B10 (0.62) | ALDH1A1TSHRSMN1; SMN2HSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252482-A2 | 7-Acyloxy-6-aminoacyloxypolyoxylabdanes, process for their preparation and their use as medicine | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-13 | — | — | EP | disclosed |