Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696710 | 0.79 | CHRM2 (0.45) | KCNH2SIGMAR1 | |
| SCHEMBL10696447 | 0.77 | PIK3CG (0.46) | — | |
| SCHEMBL10697120 | 0.76 | KDM4E (0.42) | RECQLALDH1A1 | |
| Hydrochloric Acid SCHEMBL10699302 | 0.75 | KDM4E (0.44) | RECQLALDH1A1 | |
| SCHEMBL10333960 | 0.72 | DRD4 (0.49) | DRD2DRD4SIGMAR1ALDH1A1CYP3A4 | |
| SCHEMBL9728463 | 0.71 | HTR6 (0.43) | HTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9147375 | 0.69 | ALDH1A1 (0.47) | DRD2DRD4SIGMAR1ALDH1A1CYP3A4 | |
| SCHEMBL9728514 | 0.69 | HTR6 (0.36) | HTR6DRD2SIGMAR1 | |
| SCHEMBL10698637 | 0.68 | HTR6 (0.40) | HTR6SIGMAR1 | |
| SCHEMBL29363627 | 0.66 | SIGMAR1 (0.60) | DRD2DRD4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280873-A1 | Piperidines, medicines containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-09-07 | — | — | EP | disclosed |