SCHEMBL10696737

SCHEMBL10696737

CCOC(=O)OC1CCC(OC(=O)OCC)NC1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
SOAT1 P35610 1/20 0.39
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
GAA P10253 2/20 0.31
ABL1 P00519 1/20 0.30
RIN1 Q13671 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
ALOX15 P16050 2/20 0.30
MGAM O43451 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30
PPM1B O75688 1/20 0.30
PTPN1 P18031 1/20 0.30
PPP1CC P36873 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9574624 0.84 ALDH1A1 (0.40) ALDH1A1SOAT1LMNAHSD17B10GAA
SCHEMBL4640870 0.80
SCHEMBL1078049 0.80 ALDH1A1 (0.57) ALDH1A1SOAT1LMNAHSD17B10GAA
SCHEMBL701944 0.79 ALDH1A1 (0.41) ALDH1A1SOAT1MAPT
SCHEMBL10344229 0.77 ALDH1A1 (0.52) ALDH1A1SOAT1LMNAHSD17B10GAA
SCHEMBL4014963 0.76 ALDH1A1 (0.43) ALDH1A1SOAT1LMNAHSD17B10MEN1
SCHEMBL2330898 0.76 ALDH1A1 (0.43) ALDH1A1SOAT1LMNAHSD17B10MEN1
SCHEMBL6002610 0.76 ALDH1A1 (0.39) ALDH1A1SOAT1LMNAKDM4EMAPT
SCHEMBL9038793 0.76 ALDH1A1 (0.39) ALDH1A1SOAT1LMNAKDM4EMAPT
SCHEMBL9054793 0.75 SLC6A2 (0.43) ALDH1A1SOAT1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0272594-A1 Bicyclic imides, process for their preparation and their use in crop protection HOECHST AKTIENGESELLSCHAFT (DE) 1988-06-29 EP disclosed