Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2567582 | 1.00 | SLC6A2 (0.43) | SLC6A2SLC6A3SLC6A4ALDH1A1SOAT1 | |
| SCHEMBL4014963 | 0.95 | ALDH1A1 (0.43) | SLC6A2SLC6A3SLC6A4ALDH1A1SOAT1 | |
| SCHEMBL2330898 | 0.95 | ALDH1A1 (0.43) | SLC6A2SLC6A3SLC6A4ALDH1A1SOAT1 | |
| SCHEMBL9998422 | 0.81 | EPHX1 (0.36) | SLC6A2SLC6A3SLC6A4ALDH1A1FDPS | |
| SCHEMBL27695492 | 0.80 | NAAA (0.43) | — | |
| SCHEMBL9685631 | 0.79 | SLC6A3 (0.42) | SLC6A2SLC6A3SLC6A4ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL16191692 | 0.79 | EPHX1 (0.35) | SLC6A2SLC6A3SLC6A4ALDH1A1FDPS | |
| SCHEMBL4124514 | 0.78 | KMT2A (0.44) | SLC6A2SLC6A3SLC6A4ALDH1A1KMT2A | |
| SCHEMBL9568980 | 0.78 | ALDH1A1 (0.38) | SLC6A2SLC6A3SLC6A4ALDH1A1SOAT1 | |
| Hydrochloric Acid SCHEMBL8933166 | 0.78 | SLC6A3 (0.43) | SLC6A2SLC6A3SLC6A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002517-A1 | SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |