Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 4/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL770341 | 0.68 | PTPN5 (0.34) | KIF11PTPN5 | |
| SCHEMBL16426382 | 0.64 | PTGS2 (0.54) | PTGS2KIF11GRIA4ALDH1A1 | |
| SCHEMBL8750479 | 0.64 | PTGS2 (0.54) | PTGS2GRIA4ALDH1A1CYP1A2 | |
| SCHEMBL19706344 | 0.63 | PTGS2 (0.48) | PTGS2PRCPKIF11CTSLCTSB | |
| SCHEMBL969145 | 0.63 | — | — | |
| SCHEMBL769991 | 0.63 | MAOB (0.30) | — | |
| SCHEMBL11296451 | 0.61 | PTGS2 (0.50) | PTGS2PRCPGRIA4ALDH1A1ALOX12 | |
| SCHEMBL28933413 | 0.61 | KIF11 (0.48) | PTGS2KIF11CTSLCTSBCTSS | |
| SCHEMBL17878536 | 0.61 | PTGS2 (0.50) | PTGS2GRIA4ALDH1A1 | |
| SCHEMBL12417430 | 0.61 | PTGS2 (0.50) | PTGS2PRCPGRIA4ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440520-A1 | FLUORINATED AROMATIC BIS(ACYL)-CONTAINING COMPOUNDS AND POLYESTERS PREPARED THEREFROM | 3M Innovative Properties Company (US) | 2012-04-18 | — | — | EP | disclosed |
| WO-2011005396-A1 | FLUORINATED AROMATIC BIS(ACYL)-CONTAINING COMPOUNDS AND POLYESTERS PREPARED THEREFROM | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-01-13 | — | — | WO | disclosed |