SCHEMBL770341

SCHEMBL770341

CC(F)C(F)(F)C(F)(F)OC(F)(F)c1ccc(-c2ccc(C(F)(F)OC(F)(F)C(F)(F)C(C)F)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTPN5 P54829 4/20 0.34
KIF11 P52732 6/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2223970 0.88 KIF11 (0.37) PTPN5KIF11
SCHEMBL769991 0.88 MAOB (0.30)
SCHEMBL969145 0.72
SCHEMBL1069674 0.68 PTGS2 (0.35) PTPN5KIF11
SCHEMBL12829227 0.60 TSHR (0.41) PTPN5KIF11
SCHEMBL6131444 0.59
SCHEMBL8810887 0.59
SCHEMBL12152581 0.58 ACHE (0.38) PTPN5KIF11
SCHEMBL10018707 0.58 ACHE (0.38) PTPN5KIF11
SCHEMBL25085955 0.58 HSD11B1 (0.33) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516389-B1 FLUORINATED ARYLENE-CONTAINING COMPOUNDS, METHODS, AND POLYMERS PREPARED THEREFROM 3M INNOVATIVE PROPERTIES CO (US) 2016-02-17 EP disclosed
US-9045400-B2 Fluorinated aromatic bis(acyl)-containing compounds and polyesters prepared therefrom 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-06-02 US disclosed
US-8975436-B2 Fluorinated arylene-containing compounds, methods, and polymers prepared therefrom 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-03-10 US disclosed
EP-2440520-B1 FLUORINATED AROMATIC BIS(ACYL)-CONTAINING COMPOUNDS AND POLYESTERS PREPARED THEREFROM 3M INNOVATIVE PROPERTIES CO (US) 2014-11-19 EP disclosed
US-20140163250-A1 FLUORINATED AROMATIC BIS(ACYL)-CONTAINING COMPOUNDS AND POLYESTERS PREPARED THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-06-12 US disclosed
EP-2516389-A1 FLUORINATED ARYLENE-CONTAINING COMPOUNDS, METHODS, AND POLYMERS PREPARED THEREFROM 3M Innovative Properties Company (US) 2012-10-31 EP disclosed
US-20120252997-A1 FLUORINATED ARYLENE-CONTAINING COMPOUNDS, METHODS, AND POLYMERS PREPARED THEREFROM 3M INNOVATIVE PROPERTIES COMPANY 2012-10-04 US disclosed
EP-2440520-A1 FLUORINATED AROMATIC BIS(ACYL)-CONTAINING COMPOUNDS AND POLYESTERS PREPARED THEREFROM 3M Innovative Properties Company (US) 2012-04-18 EP disclosed
US-20120071626-A1 FLUORINATED AROMATIC BIS(ACYL)-CONTAINING COMPOUNDS AND POLYESTERS PREPARED THEREFROM 3M INNOVATIVE PROPERTIES COMPANY 2012-03-22 US disclosed
WO-2011087717-A1 FLUORINATED ARYLENE-CONTAINING COMPOUNDS, METHODS, AND POLYMERS PREPARED THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-07-21 WO disclosed
WO-2011005396-A1 FLUORINATED AROMATIC BIS(ACYL)-CONTAINING COMPOUNDS AND POLYESTERS PREPARED THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140163250-A1 FLUORINATED AROMATIC BIS(ACYL)-CONTAINING COMPOUNDS AND POLYESTERS PREPARED THEREFROM NOTUM, FFAR1, FFAR2 PTPN5 2795/4885KIF11 548/4885
US-20120071626-A1 FLUORINATED AROMATIC BIS(ACYL)-CONTAINING COMPOUNDS AND POLYESTERS PREPARED THEREFROM AFF1, AFF2, FFAR2 PTPN5 3570/4885KIF11 1242/4885
US-20120252997-A1 FLUORINATED ARYLENE-CONTAINING COMPOUNDS, METHODS, AND POLYMERS PREPARED THEREFROM WASF2, PFAS, FLI1 PTPN5 2474/4885KIF11 1402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.