Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | DHFR | P00374 | 3/20 | 0.45 |
| ▸ | TYMS | P04818 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29850833 | 0.94 | ESR2 (0.65) | ESR2ESR1DHFRTYMSMAPT | |
| SCHEMBL2837044 | 0.94 | ESR2 (0.65) | ESR2ESR1DHFRTYMSMAPT | |
| SCHEMBL29967490 | 0.90 | ESR1 (0.50) | ESR2ESR1DHFRTYMSMAPT | |
| SCHEMBL2837959 | 0.90 | ESR1 (0.50) | ESR2ESR1DHFRTYMSMAPT | |
| SCHEMBL172119 | 0.82 | ESR2 (0.51) | ESR2ESR1DHFRTYMSMAPT | |
| SCHEMBL8065196 | 0.81 | AKR1C1 (0.49) | ESR2ESR1DHFRTYMSMAPT | |
| SCHEMBL29375514 | 0.78 | ESR1 (0.71) | ESR2ESR1TYMSMAPTMEN1 | |
| SCHEMBL1324119 | 0.78 | ESR1 (0.71) | ESR2ESR1TYMSMAPTMEN1 | |
| SCHEMBL24242241 | 0.76 | ESR2 (0.51) | ESR2ESR1DHFRTYMSMAPT | |
| SCHEMBL29616926 | 0.76 | ESR1 (0.58) | ESR2ESR1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274209-A1 | Glycidylethers of fluorene-containing bisphenols | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-07-13 | — | — | EP | disclosed |
| US-4707534-A | PROTECTIVE COATINGS, POLYEPOXIDES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-11-17 | — | — | US | disclosed |