Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 4/20 | 0.41 |
| ▸ | TYMS | P04818 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2837959 | 0.90 | ESR1 (0.50) | AKR1C1ESR1ESR2DHFRTYMS | |
| SCHEMBL29967490 | 0.90 | ESR1 (0.50) | AKR1C1ESR1ESR2DHFRTYMS | |
| SCHEMBL29967186 | 0.90 | AKR1C1 (0.57) | AKR1C1HSP90AA1ESR1ESR2DHFR | |
| SCHEMBL2029878 | 0.90 | AKR1C1 (0.57) | AKR1C1HSP90AA1ESR1ESR2DHFR | |
| SCHEMBL6158087 | 0.81 | ESR1 (0.58) | AKR1C1HSP90AA1ESR1ESR2DHFR | |
| SCHEMBL10696792 | 0.81 | ESR2 (0.58) | ESR1ESR2DHFRTYMSMEN1 | |
| SCHEMBL21946437 | 0.81 | AKR1C1 (0.59) | AKR1C1HSP90AA1ESR1ESR2DHFR | |
| SCHEMBL7739556 | 0.79 | ESR1 (0.59) | AKR1C1HSP90AA1ESR1ESR2DHFR | |
| SCHEMBL14198946 | 0.78 | HSP90AA1 (0.46) | AKR1C1HSP90AA1ESR1ESR2DHFR | |
| SCHEMBL2832176 | 0.73 | ESR1 (0.65) | AKR1C1HSP90AA1ESR1ESR2DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655013-B1 | GAS SEPARATIONS UTILIZING GLASSY POLYMER MEMBRANES AT SUB-AMBIENT TEMPERATURES | CYNARA CO (US) | 2000-06-14 | — | — | EP | disclosed |
| US-5837032-A | POLYMER SEPARATORS FOR GASES | THE CYNARA COMPANY (US) | 1998-11-17 | — | — | US | disclosed |
| EP-0655013-A1 | GAS SEPARATIONS UTILIZING GLASSY POLYMER MEMBRANES AT SUB-AMBIENT TEMPERATURES | THE CYNARA COMPANY Formerly RHRK Holdings, Inc. (US) | 1995-05-31 | — | — | EP | disclosed |
| WO-1994004250-A1 | GAS SEPARATIONS UTILIZING GLASSY POLYMER MEMBRANES AT SUB-AMBIENT TEMPERATURES | THE DOW CHEMICAL COMPANY (US) | 1994-03-03 | — | — | WO | disclosed |