SCHEMBL172119

SCHEMBL172119

O=C1c2ccccc2-c2ccccc2C1(c1ccc(O)c(Cl)c1)c1ccc(O)c(Cl)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 5/20 0.51
ESR1 P03372 4/20 0.51
TYMS P04818 4/20 0.49
DHFR P00374 3/20 0.49
S100A4 P26447 1/20 0.44
MAPT P10636 5/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA3 P07451 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
MEN1 O00255 5/20 0.39
KMT2A Q03164 5/20 0.39
LMNA P02545 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29850833 0.88 ESR2 (0.65) ESR2ESR1TYMSDHFRMAPT
SCHEMBL2837044 0.88 ESR2 (0.65) ESR2ESR1TYMSDHFRMAPT
SCHEMBL170122 0.82 ESR1 (0.51) ESR2ESR1TYMSDHFRS100A4
SCHEMBL172169 0.82 ESR1 (0.77) ESR2ESR1TYMSS100A4MAPT
SCHEMBL172120 0.82 ESR1 (0.51) ESR2ESR1TYMSDHFRS100A4
SCHEMBL10696792 0.82 ESR2 (0.58) ESR2ESR1TYMSDHFRMAPT
SCHEMBL13080601 0.80 ESR1 (0.52) ESR2ESR1S100A4MAPTMEN1
SCHEMBL13080606 0.80 ESR1 (0.73) ESR2ESR1S100A4MAPTMEN1
SCHEMBL171820 0.78 ESR1 (0.51) ESR2ESR1TYMSS100A4MAPT
SCHEMBL172184 0.74 S100A4 (0.50) ESR2ESR1S100A4MAPTCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8283433-B2 Polycarbonate resin and electrophotographic photosensitive body using the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-10-09 US disclosed
US-8283433-B2 Polycarbonate resin and electrophotographic photosensitive body using the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-10-09 US disclosed
EP-2048180-B1 POLYCARBONATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY USING THE SAME MITSUBISHI GAS CHEMICAL CO (JP) 2012-03-07 EP disclosed
US-20100047703-A1 POLYCARBONATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY USING THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-02-25 US disclosed
US-20100047703-A1 POLYCARBONATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY USING THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-02-25 US disclosed
EP-2048180-A1 POLYCARBONATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY USING THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2009-04-15 EP disclosed