Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695235 | 0.86 | LTA4H (0.57) | HRH3KDM4EALDH1A1LMNALTA4H | |
| SCHEMBL8973715 | 0.82 | KDM4E (0.78) | HRH3KDM4EALDH1A1LMNA | |
| SCHEMBL21780941 | 0.78 | HRH3 (0.56) | HRH3KDM4ELTA4HKDM1A | |
| SCHEMBL15834053 | 0.78 | HRH3 (0.66) | HRH3KDM4ELTA4HPSMB1PSMB5 | |
| SCHEMBL8337754 | 0.78 | HRH3 (0.70) | HRH3KDM4EALDH1A1LTA4HPSMB1 | |
| SCHEMBL10700027 | 0.78 | HRH3 (0.53) | HRH3KDM4EALDH1A1LMNALTA4H | |
| SCHEMBL10191924 | 0.78 | LTA4H (0.67) | HRH3ALDH1A1LTA4H | |
| SCHEMBL13980797 | 0.78 | LTA4H (0.67) | HRH3ALDH1A1LTA4H | |
| SCHEMBL11171280 | 0.77 | CYP2D6 (0.50) | HRH3KDM4EALDH1A1LMNALTA4H | |
| SCHEMBL10696993 | 0.77 | KDM4E (0.54) | HRH3KDM4EALDH1A1LMNALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252876-A1 | Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | claimed |
| EP-0252876-A1 | Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | disclosed |