SCHEMBL10696910

SCHEMBL10696910

CCO[Si](CCc1ccccc1)(OC)OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.39
TP53 P04637 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.36
RAB9A P51151 2/20 0.36
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
CASP1 P29466 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TAAR1 Q96RJ0 3/20 0.35
ATM Q13315 1/20 0.35
KCNH2 Q12809 2/20 0.35
CHRM2 P08172 1/20 0.35
HTR1A P08908 1/20 0.35
ADRA2A P08913 1/20 0.35
CHRM1 P11229 1/20 0.35
DRD1 P21728 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL107467 0.90 TDP1 (0.43) TDP1TP53SMN1; SMN2RAB9AALDH1A1
SCHEMBL28263028 0.89 TDP1 (0.33) TDP1TP53SMN1; SMN2RAB9ATAAR1
SCHEMBL106416 0.86 TDP1 (0.46) TDP1SMN1; SMN2RAB9AALDH1A1HPGD
SCHEMBL6332013 0.86 RAB9A (0.38) TDP1TP53SMN1; SMN2RAB9ANPC1
SCHEMBL1968087 0.84 TDP1 (0.38) TDP1SMN1; SMN2RAB9AALDH1A1HPGD
SCHEMBL1765960 0.84 TDP1 (0.47) TDP1SMN1; SMN2RAB9AALDH1A1HPGD
SCHEMBL2488885 0.84 HTR2A (0.42) TDP1SMN1; SMN2TAAR1AOC3CYP2A6
SCHEMBL7554332 0.83 TDP1 (0.40) TDP1TP53RAB9AALDH1A1HPGD
SCHEMBL1972960 0.83 LMNA (0.39) TDP1SMN1; SMN2RAB9AALDH1A1TAAR1
SCHEMBL28065352 0.82 RAB9A (0.38) TDP1TP53SMN1; SMN2RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107670690-A A kind of iron-based cyano-containing anion imidazole ion liquid catalyst and its preparation method and application 常州大学 2018-02-09 CN disclosed
CN-107597184-A A kind of preparation method and application of iron-based pyrrolidonium ionic liquids catalyst 常州大学 2018-01-19 CN disclosed
CN-1880400-B Adhesive SUMITOMO CHEMICAL CO 2010-04-21 CN disclosed
CN-1880400-A Adhesive SUMITOMO CHEMICAL CO (JP) 2006-12-20 CN disclosed
US-4769308-A Dry presensitized plate with photosensitive layer containing organotin FUJI PHOTO FILM CO., LTD. (JP) 1988-09-06 US disclosed