SCHEMBL1069693

SCHEMBL1069693

CO[SiH](OC)C(CC(C)C)NC(N)=O

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.34
MME P08473 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CTSC P53634 1/20 0.33
ALDH1A1 P00352 2/20 0.32
RNPEP Q9H4A4 1/20 0.32
SLC7A5 Q01650 1/20 0.32
BIRC2 Q13490 1/20 0.32
CAD P27708 1/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31
TAS1R3 Q7RTX0 1/20 0.30
TAS1R1 Q7RTX1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL963464 0.78 CAD (0.34) BIRC2CADTAS1R3TAS1R1
SCHEMBL2460038 0.74 CA12 (0.33) SMN1; SMN2ALDH1A1CAD
SCHEMBL17650 0.71 ALDH1A1 (0.33) ALDH1A1
SCHEMBL28750770 0.69 FOLH1 (0.56) FOLH1SMN1; SMN2BIRC2TAS1R3TAS1R1
SCHEMBL27574600 0.69 SLC7A5 (0.41) SMN1; SMN2ALDH1A1RNPEPSLC7A5MEN1
SCHEMBL27782411 0.69 SLC7A5 (0.41) SMN1; SMN2ALDH1A1RNPEPSLC7A5MEN1
SCHEMBL9555383 0.69 SLC7A5 (0.41) SMN1; SMN2ALDH1A1RNPEPSLC7A5MEN1
SCHEMBL962551 0.68
SCHEMBL10695911 0.68
SCHEMBL11662658 0.67 SLC7A5 (0.39) SMN1; SMN2ALDH1A1RNPEPSLC7A5MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2147041-A2 METHOD OF APPLYING AN ANTI-CORROSION AND/OR ADHESION PROMOTING COATING TO A METAL AND RESULTING COATED METAL Momentive Performance Materials Inc. (US) 2010-01-27 EP claimed
WO-2008133916-A2 METHOD OF APPLYING AN ANTI-CORROSION AND/OR ADHESION PROMOTING COATING TO A METAL AND RESULTING COATED METAL MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-11-06 WO claimed
US-20080268162-A1 Method of applying an anti-corrosion and/or adhesion promoting coating to a metal and resulting coated metal MOMENTIVE PERFORMANCE MATERIALS INC. 2008-10-30 US claimed
EP-2147041-B1 METHOD OF APPLYING AN ANTI-CORROSION AND/OR ADHESION PROMOTING COATING TO A METAL AND RESULTING COATED METAL MOMENTIVE PERFORMANCE MAT INC (US) 2017-08-23 EP disclosed
US-8501314-B2 Method of applying an anti-corrosion and/or adhesion promoting coating to a metal and resulting coated metal MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-08-06 US disclosed
US-20110111212-A1 Method of Applying An Anti-Corrosion And/Or Adhesion Promoting Coating To A Metal And Resulting Coated Metal MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-05-12 US disclosed
US-7875318-B2 Hydrolyzing partially or completely hydrolyzed silane possessing one or more hydroxyl groups; bis-(hydroxyethyl)aminopropyltriethoxysilane; chromium free; nontoxic; environmentally friendly MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-01-25 US disclosed
US-20080268162-A1 Method of applying an anti-corrosion and/or adhesion promoting coating to a metal and resulting coated metal MOMENTIVE PERFORMANCE MATERIALS INC. 2008-10-30 US disclosed