SCHEMBL17650

SCHEMBL17650

CO[SiH](OC)C(CC(C)C)NC(C)N

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9323811 0.81
SCHEMBL6071774 0.80 ALDH1A1 (0.31) ALDH1A1TSHRMAPK1
SCHEMBL2132181 0.78
SCHEMBL10893879 0.78
SCHEMBL962551 0.72
SCHEMBL10695911 0.72
Ammonia Solution, Strong SCHEMBL21048943 0.71
SCHEMBL1069693 0.71 FOLH1 (0.34) ALDH1A1
SCHEMBL1070706 0.70 TSHR (0.41) ALDH1A1TSHRMAPK1
SCHEMBL8134330 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114917685-A Composite filtering material capable of effectively blocking PM2.5 and application of composite filtering material in protective mask 青岛海诺生物工程有限公司 2022-08-19 CN claimed
CN-110773165-B Preparation method of catalyst for synthesizing ethylene glycol by dimethyl oxalate hydrogenation 中催技术有限公司 2022-07-08 CN claimed
CN-113003675-A Mxene material with organic chelating functional group grafted on surface and preparation method thereof 南方科技大学 2021-06-22 CN claimed
CN-110773165-A Preparation method of catalyst for synthesizing ethylene glycol by dimethyl oxalate hydrogenation 中催技术有限公司 2020-02-11 CN claimed
EP-3049483-B1 METAL EFFECT PIGMENTS MODIFIED WITH A SILANE LAYER CONTAINING AT LEAST TWO DIFFERENT BIFUNCTIONAL SILANES SCHLENK METALLIC PIGMENTS GMBH (DE) 2019-06-12 EP claimed
US-20160244615-A1 METAL EFFECT PIGMENTS MODIFIED WITH A SILANE LAYER CONTAINING AT LEAST TWO DIFFERENT BIFUNCTIONAL SILANES SCHLENK METALLIC PIGMENTS GMBH (DE) 2016-08-25 US claimed
EP-3049483-A1 METAL EFFECT PIGMENTS MODIFIED WITH A SILANE LAYER CONTAINING AT LEAST TWO DIFFERENT BIFUNCTIONAL SILANES Schlenk Metallic Pigments GmbH (DE) 2016-08-03 EP claimed
US-9175187-B2 Self-etching cementitious substrate coating composition VALSPAR SOURCING, INC. (US) 2015-11-03 US claimed
WO-2015044188-A1 METAL EFFECT PIGMENTS MODIFIED WITH A SILANE LAYER CONTAINING AT LEAST TWO DIFFERENT BIFUNCTIONAL SILANES SCHLENK METALLIC PIGMENTS GMBH (DE) 2015-04-02 WO claimed
US-8697020-B2 Silica magnetic particles having a spherical form and a process for preparing the same BIONEER CORPORATION (KR) 2014-04-15 US claimed
EP-2326691-A2 SELF-ETCHING CEMENTITIOUS SUBSTRATE COATING COMPOSITION Valspar Sourcing, Inc. (US) 2011-06-01 EP claimed
US-20110054162-A1 Silica Magnetic Particles Having a Spherical Form and a Process for Preparing the Same BIONEER CORPORATION (KR) 2011-03-03 US claimed
WO-2010019825-A2 SELF-ETCHING CEMENTITIOUS SUBSTRATE COATING COMPOSITION VALSPAR SOURCING, INC. (US) 2010-02-18 WO claimed
WO-2009102171-A2 SILICA MAGNETIC PARTICLES HAVING A SPHERICAL FORM AND A PROCESS FOR PREPARING THE SAME BIONEER CORPORATION (KR) 2009-08-20 WO claimed
EP-1945750-A2 MICROARRAY HAVING A BASE CLEAVABLE SUCINATE LINKER Combimatrix Corporation (US) 2008-07-23 EP claimed
US-20080125327-A1 Bonding amino moieties to solid surface with reactive hydroxyl groups, bonding succinate moieties to the amine groups through amide bonds to form cleavable linkers attached to the solid surface, bonding a succinate group, a sugar group and a base group, synthesizing oligonucleotides CUSTOMARRAY, INC. 2008-05-29 US claimed
WO-2007035500-A2 MICROARRAY HAVING A BASE CLEAVABLE SUCCINATE LINKER COMBIMATRIX CORPORATION (US) 2007-03-29 WO claimed
US-20070065877-A1 Microarray having a base cleavable succinate linker COMBIMATRIX CORPORATION 2007-03-22 US claimed
EP-1116813-A1 Hydrophilic softener for textiles comprising epoxy glycol siloxane polymers and amine funtional materials DOW CORNING CORPORATION (US) 2001-07-18 EP claimed
US-5852110-A Method for making amino functional polysiloxane emulsions DOW CORNING CORPORATION (US) 1998-12-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054162-A1 Silica Magnetic Particles Having a Spherical Form and a Process for Preparing the Same SPIN3, SPIN1, SPIN4 ALDH1A1 4230/4885TSHR 3959/4885MAPK1 2187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.