Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.54 |
| ▸ | AHR | P35869 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10695546 | 0.87 | HDAC1 (0.65) | POLBMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL10695460 | 0.82 | NAMPT (0.59) | POLBMEN1KMT2ARAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL10696995 | 0.81 | KDM4E (0.63) | POLBGAAMEN1KMT2ARAB9A | |
| SCHEMBL31467959 | 0.80 | GAA (0.80) | POLBGAAMEN1KMT2ARAB9A | |
| SCHEMBL8970981 | 0.79 | PTK2 (0.70) | GAAMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL10696004 | 0.79 | NAMPT (0.59) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL10694055 | 0.79 | NAMPT (0.59) | GAAKMT2ARAB9ANPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10694072 | 0.79 | TSHR (0.58) | POLBGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL10696924 | 0.79 | NAMPT (0.65) | POLBMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7300821 | 0.76 | RAB9A (0.66) | POLBGAAMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268267-A2 | Guanidinomethylbenzoic acid derivatives, compositions containing the same, processes for preparing the same, and the use of the same in the manufacture of medicaments of therapeutic value | NIPPON HYPOX LABORATORIES INCORPORATED (JP) | 1988-05-25 | — | — | EP | disclosed |