Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 14/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697890 | 0.82 | ABCC9 (0.41) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL10696025 | 0.82 | ABCC9 (0.37) | ABCC9ALDH1A1MAPTABCC8KCNJ11 | |
| SCHEMBL9315191 | 0.81 | ABCC9 (0.58) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL7275528 | 0.81 | ABCC9 (0.58) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9315187 | 0.81 | ABCC9 (0.58) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL8084937 | 0.80 | ABCC9 (0.50) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL8088383 | 0.80 | ALDH1A1 (0.36) | ABCC9ALDH1A1MAPTNPSR1LMNA | |
| SCHEMBL10696822 | 0.80 | ABCC9 (0.38) | ABCC9ALDH1A1MAPTABCC8KCNJ11 | |
| SCHEMBL10696640 | 0.80 | ABCC9 (0.48) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL10696820 | 0.79 | ABCC9 (0.39) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273262-A2 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |