Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698562 | 0.93 | TDP1 (0.34) | POLBMAPTNPSR1TSHRTXNRD1 | |
| SCHEMBL10696523 | 0.81 | MAPT (0.36) | POLBMAPTNPSR1TSHRTXNRD1 | |
| SCHEMBL10696364 | 0.79 | EPAS1 (0.36) | POLBMAPTNPSR1TSHRTXNRD1 | |
| SCHEMBL10696669 | 0.78 | POLB (0.39) | POLBMAPTNPSR1SMN1; SMN2TXNRD1 | |
| SCHEMBL10698683 | 0.78 | TDP1 (0.44) | POLBMAPTNPSR1TSHRSMN1; SMN2 | |
| SCHEMBL10696869 | 0.76 | TDP1 (0.41) | POLBMAPTNPSR1TSHRSMN1; SMN2 | |
| SCHEMBL10698177 | 0.75 | TDP1 (0.36) | POLBMAPTNPSR1TSHRTXNRD1 | |
| SCHEMBL10698045 | 0.74 | POLB (0.39) | POLBMAPTNPSR1TSHRSMN1; SMN2 | |
| SCHEMBL10702678 | 0.72 | POLB (0.37) | POLBMAPTNPSR1TSHRTXNRD1 | |
| SCHEMBL898028 | 0.71 | ALDH1A1 (0.42) | POLBMAPTNPSR1TSHRTXNRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |