Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 2/20 | 0.36 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.35 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698177 | 0.92 | TDP1 (0.36) | EPAS1VEGFATDP1TSHRALDH1A1 | |
| SCHEMBL10696278 | 0.90 | EPAS1 (0.37) | EPAS1VEGFATDP1TSHRALDH1A1 | |
| SCHEMBL10698683 | 0.84 | TDP1 (0.44) | TDP1TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL10696869 | 0.82 | TDP1 (0.41) | EPAS1TDP1TSHRALDH1A1CYP3A4 | |
| SCHEMBL10698562 | 0.82 | TDP1 (0.34) | EPAS1VEGFATDP1TSHRALDH1A1 | |
| SCHEMBL10702678 | 0.80 | POLB (0.37) | EPAS1VEGFATDP1TSHRALDH1A1 | |
| SCHEMBL10697019 | 0.79 | POLB (0.36) | TSHRALDH1A1TXNRD1MAPTNPSR1 | |
| SCHEMBL10697964 | 0.78 | KDM4E (0.40) | TDP1ALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL10696298 | 0.77 | ALDH1A1 (0.34) | TDP1TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL10696669 | 0.77 | POLB (0.39) | EPAS1VEGFATDP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |