Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | POLB | P06746 | 7/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10708358 | 0.91 | MEN1 (0.52) | MEN1KMT2APOLBBLMCTDSP1 | |
| SCHEMBL10696515 | 0.86 | NPC1 (0.50) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL10694162 | 0.85 | KMT2A (0.38) | MEN1KMT2APOLBMAPTPKM | |
| SCHEMBL10699652 | 0.84 | NPC1 (0.49) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL10698900 | 0.81 | NPC1 (0.52) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL10697943 | 0.79 | MAPT (0.41) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL2490357 | 0.79 | MAPT (0.56) | MEN1KMT2AMAPTALDH1A1PKM | |
| SCHEMBL10696939 | 0.77 | SMN1; SMN2 (0.49) | MEN1KMT2APOLBKDM4EMAPT | |
| SCHEMBL10717276 | 0.77 | NPC1 (0.53) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL10698960 | 0.77 | MAPT (0.41) | MEN1KMT2AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |