Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.50 |
| ▸ | NOS1 | P29475 | 2/20 | 0.50 |
| ▸ | NOS2 | P35228 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9292438 | 0.80 | NOS3 (0.57) | NOS3NOS1NOS2CA12CA1 | |
| SCHEMBL69865 | 0.79 | RAB9A (0.65) | CA12CA1CA2CA6CA9 | |
| SCHEMBL69866 | 0.79 | RAB9A (0.65) | CA12CA1CA2CA6CA9 | |
| SCHEMBL31045928 | 0.79 | RAB9A (0.65) | CA12CA1CA2CA6CA9 | |
| SCHEMBL6512127 | 0.78 | CA12 (0.54) | NOS3NOS1NOS2CA12CA1 | |
| SCHEMBL9676480 | 0.78 | CA12 (0.54) | NOS3NOS1NOS2CA12CA1 | |
| SCHEMBL1737568 | 0.77 | NOS3 (0.62) | NOS3NOS1NOS2CA12CA1 | |
| SCHEMBL23554009 | 0.77 | RAB9A (0.55) | NOS3NOS1NOS2CA12CA1 | |
| SCHEMBL834716 | 0.77 | NOS3 (0.48) | NOS3NOS1MAPTRAB9ANPC1 | |
| Isophthalic Acid SCHEMBL123940 | 0.77 | CA12 (0.62) | CA12CA1CA2CA6CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268343-A2 | Enzymatic process for 3-substituted cephalosporins | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 1988-05-25 | — | — | EP | disclosed |