Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.48 |
| ▸ | NOS1 | P29475 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4993304 | 0.78 | TRPA1 (0.46) | NOS3NOS1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL342606 | 0.78 | TRPA1 (0.46) | NOS3NOS1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5699982 | 0.77 | TDP1 (0.54) | MAPTRAB9ASMN1; SMN2NPC1CES2 | |
| SCHEMBL5470032 | 0.77 | AKR1C3 (0.51) | MAPTRAB9AALDH1A1POLBCYP2D6 | |
| SCHEMBL7438431 | 0.77 | HPGD (0.42) | NOS3NOS1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL10697128 | 0.77 | NOS3 (0.50) | NOS3NOS1MAPTRAB9ASMN1; SMN2 | |
| Azobenzene SCHEMBL29154401 | 0.76 | ALDH1A1 (0.67) | NOS3NOS1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL4829863 | 0.76 | TRPA1 (0.44) | NOS3NOS1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL10376096 | 0.75 | MAPT (0.52) | NOS3NOS1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL10509447 | 0.75 | PLG (0.43) | NOS3NOS1SMN1; SMN2ALDH1A1NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 894 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114437046-A | 5-fluorouracil spliced 4-aniline quinazoline compound and preparation method and application thereof | 遵义医药高等专科学校 | 2022-05-06 | — | — | CN | claimed |
| CN-114437161-A | Zidovudine spliced 4-aniline quinazoline compound as well as preparation method and application thereof | 遵义医药高等专科学校 | 2022-05-06 | — | — | CN | claimed |
| US-9198426-B2 | Use of 5 pyridin-4-yl-1,3-thiazoles for controlling phytopathogenic fungi | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | claimed |
| EP-1962830-B1 | AZAINDOLE INHIBITORS OF AURORA KINASES | GLAXOSMITHKLINE LLC (US) | 2013-03-27 | — | — | EP | claimed |
| EP-2378880-A1 | USE OF 5-PYRIDIN-4YL(1,3)THIAZOLE FOR TREATING PHYTOPATHOGENIC FUNGI | BAYER CROPSCIENCE AG (DE) | 2011-10-26 | — | — | EP | claimed |
| US-20100168185-A1 | Use of 5-pyridin-4-yl-1,3-thiazoles for controlling phytopathogenic fungi | BAYER CORPSCIENCE AG (DE) | 2010-07-01 | — | — | US | claimed |
| WO-2010069494-A1 | USE OF 5-PYRIDIN-4YL(1,3)THIAZOLE FOR TREATING PHYTOPATHOGENIC FUNGI | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-06-24 | — | — | WO | claimed |
| EP-2198710-A1 | Use of 5-pyridin-4yl-(1,3) thiazoles for combating phytopathogenic fungi | Bayer CropScience AG (DE) | 2010-06-23 | — | — | EP | claimed |
| US-7495102-B2 | Azaindole inhibitors of aurora kinases | SMITHKLINE BEECHAM CORPORATION (US) | 2009-02-24 | — | — | US | claimed |
| EP-1962830-A2 | AZAINDOLE INHIBITORS OF AURORA KINASES | SmithKline Beecham Corporation (US) | 2008-09-03 | — | — | EP | claimed |
| US-H122-H | PYRAZOLOAZOLE-TYPE MAGENTA COUPLER DISPERSED IN A HIGH-BOILING PHOSPHATE SOLVENT | FUJI PHOTO FILM CO., LTD. (JP) | 1986-09-02 | — | — | US | claimed |
| US-4587207-A | A-ACYL-A-PHENOXYACETANILIDE TYPE YELLOW COUPLER HAVING AN M-SULFAMOLY GROUP | FUJI PHOTO FILM CO., LTD. (JP) | 1986-05-06 | — | — | US | claimed |
| EP-0170164-A2 | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1986-02-05 | — | — | EP | claimed |
| EP-0001841-B1 | TYLOSIN DERIVATIVES | SANRAKU-OCEAN CO., LTD. (JP) | 1982-12-01 | — | — | EP | claimed |
| US-4293691-A | Method for preparing magenta couplers having thioether groups | FUJI PHOTO FILM CO., LTD. (JP) | 1981-10-06 | — | — | US | claimed |
| US-4218557-A | PROTECTIVE COATINGS, MOLDINGS, FOAMS | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-08-19 | — | — | US | claimed |
| US-4205163-A | Tylosin derivatives | SANRAKU-OCEAN CO., LTD. (JP) | 1980-05-27 | — | — | US | claimed |
| EP-0010231-A1 | Polyphosphazene polymers containing N-substituted amido and imido substituents and process for their preparation | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1980-04-30 | — | — | EP | claimed |
| EP-0001841-A2 | Tylosin derivatives | SANRAKU-OCEAN CO., LTD. (JP) | 1979-05-16 | — | — | EP | claimed |
| US-4122089-A | Aminothiofluoran compounds, process for the production thereof, and recording elements containing the same | SANKIO CHEMICAL CO., LTD. (JP) | 1978-10-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168185-A1 | Use of 5-pyridin-4-yl-1,3-thiazoles for controlling phytopathogenic fungi | PIR, PNPO, PDXK | NOS3 1470/4885NOS1 2345/4885MAPT 711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.