Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518617 | 0.89 | FOLH1 (0.51) | FOLH1LTB4R2KMT2AMEN1GAA | |
| SCHEMBL3233824 | 0.81 | FOLH1 (0.55) | FOLH1LTB4R2LTB4RKMT2APTPN11 | |
| SCHEMBL3236901 | 0.80 | FOLH1 (0.54) | FOLH1LTB4R2LTB4RKMT2APTPN11 | |
| SCHEMBL901518 | 0.79 | NR1H4 (0.41) | RXRARXRBRXRGKMT2AMEN1 | |
| SCHEMBL30461149 | 0.77 | FOLH1 (0.71) | FOLH1LTB4R2LTB4RKMT2AMEN1 | |
| SCHEMBL3234271 | 0.77 | FOLH1 (0.71) | FOLH1LTB4R2LTB4RKMT2AMEN1 | |
| SCHEMBL3466168 | 0.72 | FOLH1 (0.55) | FOLH1LTB4R2KMT2APTPN11CES2 | |
| SCHEMBL27890311 | 0.72 | CYP4F2 (0.40) | FOLH1KMT2AMEN1GAACES2 | |
| SCHEMBL7132396 | 0.71 | ALDH1A1 (0.47) | FOLH1GAAPTPN11 | |
| SCHEMBL1072566 | 0.70 | FOLH1 (0.39) | FOLH1LTB4R2LTB4RRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445888-B1 | Process for preparing telmisartan | INKE SA (ES) | 2013-08-07 | — | — | EP | disclosed |
| EP-2445888-A1 | PROCESS FOR PREPARING TELMISARTAN | INKE, S.A. (ES) | 2012-05-02 | — | — | EP | disclosed |
| EP-2277866-A1 | Process for preparing telmisartan | INKE, S.A. (ES) | 2011-01-26 | — | — | EP | disclosed |
| WO-2010149565-A1 | PROCESS FOR PREPARING TELMISARTAN | INKE, S.A. (ES) | 2010-12-29 | — | — | WO | disclosed |