Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.40 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3233824 | 0.84 | FOLH1 (0.55) | FOLH1LTB4R2LTB4RKMT2APTPN11 | |
| SCHEMBL1069725 | 0.80 | FOLH1 (0.51) | FOLH1LTB4R2LTB4RKMT2APTPN11 | |
| SCHEMBL30461149 | 0.80 | FOLH1 (0.71) | FOLH1LTB4R2LTB4RKMT2ACES2 | |
| SCHEMBL3234271 | 0.80 | FOLH1 (0.71) | FOLH1LTB4R2LTB4RKMT2ACES2 | |
| SCHEMBL200520 | 0.79 | CYP4F2 (0.44) | KMT2ACYP4F2CYP4A11CES2CES1 | |
| SCHEMBL7843765 | 0.79 | FOLH1 (0.56) | FOLH1LTB4R2KMT2APTPN11CLCN2 | |
| SCHEMBL3466168 | 0.75 | FOLH1 (0.55) | FOLH1LTB4R2KMT2APTPN11CES2 | |
| SCHEMBL8518617 | 0.74 | FOLH1 (0.51) | FOLH1LTB4R2KMT2APTPN11 | |
| SCHEMBL8329762 | 0.74 | FOLH1 (0.54) | FOLH1KMT2A | |
| SCHEMBL29236562 | 0.74 | FOLH1 (0.67) | FOLH1LTB4R2LTB4RPTPN11METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018441-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF SUBSTANTIALLY PURE TELMISARTAN | CADILA PHARMACEUTICALS LTD. (IN) | 2010-02-18 | — | — | WO | claimed |