Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | LTB4R | Q15722 | 8/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 8/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50454 | 0.83 | LMNA (0.80) | LMNAHSD17B10ALDH1A1SMN1; SMN2MITF | |
| Hydrochloric Acid SCHEMBL3647676 | 0.82 | LMNA (0.77) | LMNAHSD17B10ALDH1A1SMN1; SMN2MITF | |
| SCHEMBL6426219 | 0.81 | LMNA (0.59) | LMNAHSD17B10LTB4RLTB4R2ALDH1A1 | |
| SCHEMBL4100247 | 0.81 | LMNA (0.59) | LMNAHSD17B10LTB4RLTB4R2ALDH1A1 | |
| SCHEMBL5114421 | 0.80 | LMNA (0.69) | LMNAHSD17B10ALDH1A1SMN1; SMN2MITF | |
| SCHEMBL9774496 | 0.77 | LMNA (0.87) | LMNAHSD17B10ALDH1A1SMN1; SMN2MITF | |
| SCHEMBL12134361 | 0.77 | LMNA (0.61) | LMNAHSD17B10ALDH1A1SMN1; SMN2MITF | |
| SCHEMBL9641793 | 0.76 | LTB4R (0.66) | LTB4RLTB4R2FFAR1ALOX5S1PR5 | |
| SCHEMBL10148419 | 0.76 | KMT2A (0.65) | LTB4RLTB4R2FFAR1ALOX5S1PR5 | |
| SCHEMBL10182834 | 0.76 | LTB4R (0.61) | LTB4RLTB4R2FFAR1ALOX5S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279281-A2 | Lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1988-08-24 | — | — | EP | disclosed |