Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 7/20 | 0.34 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10711807 | 0.86 | ALDH1A1 (0.35) | ALDH1A1KCNMA1NPC1RAB9AMAPT | |
| SCHEMBL10708574 | 0.83 | ALDH1A1 (0.37) | ALDH1A1KCNMA1NPC1RAB9AMAPT | |
| SCHEMBL10697763 | 0.82 | ALDH1A1 (0.34) | ALDH1A1KCNMA1NPC1RAB9AMAPT | |
| SCHEMBL10699685 | 0.78 | NPC1 (0.39) | ALDH1A1NPC1RAB9AMAPTKMT2A | |
| SCHEMBL10530439 | 0.77 | PGR (0.36) | ALDH1A1KCNMA1NPC1RAB9AMAPT | |
| SCHEMBL10709623 | 0.76 | ALDH1A1 (0.34) | ALDH1A1NPC1RAB9AMAPTKMT2A | |
| SCHEMBL2488921 | 0.76 | LMNA (0.51) | ALDH1A1NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL10709164 | 0.75 | MAPT (0.52) | ALDH1A1NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL10532295 | 0.75 | PGR (0.37) | ALDH1A1KCNMA1NPC1RAB9AMAPT | |
| SCHEMBL10699188 | 0.75 | SETD7 (0.44) | ALDH1A1NPC1RAB9AMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |