Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CTSC | P53634 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.41 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3194551 | 0.84 | MAPT (0.61) | MAPTEPHX2CHRNA7L3MBTL1KDM4E | |
| SCHEMBL1923201 | 0.84 | MAPT (0.61) | MAPTEPHX2CHRNA7L3MBTL1KDM4E | |
| SCHEMBL1921523 | 0.79 | KIF11 (0.61) | MAPTEPHX2CHRNA7L3MBTL1KDM4E | |
| SCHEMBL11125111 | 0.77 | CTSC (0.56) | MAPTEPHX2L3MBTL1KDM4EMEN1 | |
| SCHEMBL15146260 | 0.76 | MAPT (0.56) | MAPTEPHX2L3MBTL1KDM4EMEN1 | |
| SCHEMBL9073469 | 0.76 | MAPT (0.68) | MAPTEPHX2CHRNA7L3MBTL1KDM4E | |
| SCHEMBL9070626 | 0.76 | MAPT (0.52) | MAPTEPHX2CHRNA7L3MBTL1KDM4E | |
| SCHEMBL5470709 | 0.75 | DHODH (0.52) | MAPTEPHX2L3MBTL1KDM4EMEN1 | |
| SCHEMBL5543407 | 0.74 | MAPT (0.50) | MAPTEPHX2L3MBTL1KDM4EMEN1 | |
| SCHEMBL12282928 | 0.73 | TSHR (0.41) | MAPTEPHX2L3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278673-A2 | A benzoylurea derivative and its production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-08-17 | — | — | EP | disclosed |