Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12294729 | 0.79 | DHFR (0.43) | MAPTEPHX2KDM4ENISCHDHFR | |
| SCHEMBL254957 | 0.76 | MAPT (0.56) | TSHRMAPTEPHX2KDM4ENISCH | |
| SCHEMBL29268186 | 0.75 | EPHX2 (0.41) | MAPTEPHX2KDM4ENISCHMAOB | |
| SCHEMBL2056111 | 0.74 | ALDH1A1 (0.50) | TSHRMAPTEPHX2ALDH1A1DHFR | |
| SCHEMBL8386558 | 0.73 | EPHX2 (0.47) | TSHRMAPTEPHX2KDM4ESERPINE1 | |
| SCHEMBL10697279 | 0.73 | MAPT (0.47) | TSHRMAPTEPHX2KDM4EALDH1A1 | |
| SCHEMBL28980342 | 0.72 | EPHX2 (0.46) | TSHREPHX2DHFRSERPINE1SLC6A4 | |
| SCHEMBL15521000 | 0.71 | CA1 (0.52) | MAPTKDM4EAOC3ALDH1A1L3MBTL1 | |
| SCHEMBL16710496 | 0.71 | SERPINE1 (0.47) | MAPTEPHX2KDM4EALDH1A1GPR3 | |
| SCHEMBL9091199 | 0.71 | SERPINE1 (0.47) | MAPTEPHX2KDM4EALDH1A1GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9024041-B2 | P38 MAP kinase inhibitors | RESPIVERT LTD. (GB) | 2015-05-05 | — | — | US | disclosed |
| US-20130040962-A1 | P38 MAP Kinase Inhibitors | RESPIVERT LTD (GB) | 2013-02-14 | — | — | US | disclosed |
| WO-2011124930-A1 | P38 MAP KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2011-10-13 | — | — | WO | disclosed |
| CN-1025811-C | Pesticidal method using N-phenyl pyrazoles | MAY & BAKER LTD (GB) | 1994-09-07 | — | — | CN | disclosed |
| CN-1025582-C | Azole pesticides | SCHERING AGROCHEMICALS LTD (GB) | 1994-08-10 | — | — | CN | disclosed |
| CN-1049341-A | AZOLE PESTICIDES | SCHERING AGROCHEMICALS LTD (GB) | 1991-02-20 | — | — | CN | disclosed |
| CN-86108643-A | Insecticidal method using N-phenylpyrazoles | — | 1987-07-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130040962-A1 | P38 MAP Kinase Inhibitors | MAPK15, MAPK1, MAP3K15 | TSHR 3231/4885MAPT 890/4885EPHX2 2144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.