SCHEMBL10697289

SCHEMBL10697289

C=CCN(CC=C)c1ccc(-c2nc3ccccc3nc2-c2ccc(N(CC=C)CC=C)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.43
L3MBTL1 Q9Y468 5/20 0.43
LMNA P02545 4/20 0.43
GAA P10253 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
ALDH1A1 P00352 4/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
HPGD P15428 1/20 0.41
CYP2C19 P33261 1/20 0.41
MAPK10 P53779 1/20 0.40
MAPK14 Q16539 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
RAD51 Q06609 1/20 0.39
AKT1 P31749 1/20 0.38
AKT2 P31751 1/20 0.38
DHFR P00374 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9811796 0.78 ALDH1A1 (0.43) L3MBTL1LMNAMEN1KMT2AALDH1A1
SCHEMBL6040036 0.78 DHFR (0.45) KDM4EL3MBTL1LMNAMEN1KMT2A
SCHEMBL6692403 0.78 CHKA (0.46) LMNAGAAALDH1A1CYP1A2HPGD
SCHEMBL9811812 0.76 NPC1 (0.54) KDM4EMEN1KMT2AALDH1A1HPGD
SCHEMBL851567 0.75 CHKA (0.50) L3MBTL1GAATDP1ALDH1A1CYP1A2
SCHEMBL83762 0.73 CHKA (0.46) KDM4EGAAMEN1KMT2AALDH1A1
SCHEMBL11032897 0.73 CHKA (0.46) KDM4EGAAMEN1KMT2AALDH1A1
SCHEMBL10697286 0.73 ALDH1A1 (0.42) KDM4EL3MBTL1LMNAGAAMEN1
Hydrochloric Acid SCHEMBL4050783 0.72 CHKA (0.44) KDM4EGAAMEN1KMT2ACYP1A2
Ammonia Solution, Strong SCHEMBL7942696 0.72 CHKA (0.44) KDM4ELMNAGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4760006-A Photoconductive layer containing photoconductor, a binder and a sensitizing dyestuff on electroconductive support HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-26 US claimed
EP-0166230-B1 2,3-BIS(DIALKYLAMINOPHENYL)QUINOXALINES AND THEIR USE IN ELECTROGRAPHIC RECORDING MATERIALS HOECHST AKTIENGESELLSCHAFT (DE) 1988-04-06 EP claimed
US-4760006-A Photoconductive layer containing photoconductor, a binder and a sensitizing dyestuff on electroconductive support HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-26 US disclosed
US-4760006-A Photoconductive layer containing photoconductor, a binder and a sensitizing dyestuff on electroconductive support HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-26 US disclosed
US-4760006-A Photoconductive layer containing photoconductor, a binder and a sensitizing dyestuff on electroconductive support HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-26 US disclosed
EP-0166230-A1 2,3-Bis(dialkylaminophenyl)quinoxalines and their use in electrographic recording materials HOECHST AKTIENGESELLSCHAFT (DE) 1986-01-02 EP disclosed