Sugi Predict

Sugi Predict / Compounds / SCHEMBL10697286

SCHEMBL10697286

SCHEMBL10697286

C=CCN(CC=C)c1ccccc1-c1nc2ccccc2nc1-c1ccccc1N(CC=C)CC=C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.42
▸ MAPT P10636 4/20 0.41
▸ SMN1; SMN2 Q16637 3/20 0.41
▸ NPC1 O15118 2/20 0.41
▸ RAB9A P51151 2/20 0.41
▸ AHR P35869 1/20 0.41
▸ HPGD P15428 4/20 0.38
▸ POLB P06746 2/20 0.38
▸ PKM P14618 2/20 0.38
▸ KDM4E B2RXH2 4/20 0.37
▸ LMNA P02545 1/20 0.37
▸ GAA P10253 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ PDE4B Q07343 1/20 0.36
▸ PDE4D Q08499 1/20 0.36
▸ MEN1 O00255 2/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ GLA P06280 1/20 0.35
▸ HIF1A Q16665 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11667380 0.75 ADRB2 (0.37) ALDH1A1SMN1; SMN2HPGDPOLBKDM4E
SCHEMBL10697289 0.73 KDM4E (0.43) ALDH1A1HPGDPKMKDM4ELMNA
SCHEMBL7717165 0.71 PTPN1 (0.37) ALDH1A1SMN1; SMN2NPC1RAB9AHPGD
SCHEMBL8520461 0.70 RAB9A (0.55) ALDH1A1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL27630865 0.70 ALDH1A1 (0.46) ALDH1A1MAPTNPC1RAB9AHPGD
SCHEMBL3631013 0.69 C5AR1 (0.38) ALDH1A1SMN1; SMN2NPC1RAB9AHPGD
SCHEMBL2489961 0.69 MAPT (0.73) ALDH1A1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL4872477 0.68 NPC1 (0.31) ALDH1A1NPC1RAB9AHPGDPOLB
SCHEMBL4557934 0.68 ALDH1A1 (0.46) ALDH1A1MAPTHPGDPOLBKDM4E
SCHEMBL5338489 0.68 ALDH1A1 (0.34) ALDH1A1MAPTSMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4760006-A Photoconductive layer containing photoconductor, a binder and a sensitizing dyestuff on electroconductive support HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-26 — — US claimed
EP-0166230-B1 2,3-BIS(DIALKYLAMINOPHENYL)QUINOXALINES AND THEIR USE IN ELECTROGRAPHIC RECORDING MATERIALS HOECHST AKTIENGESELLSCHAFT (DE) 1988-04-06 — — EP claimed
EP-0166230-A1 2,3-Bis(dialkylaminophenyl)quinoxalines and their use in electrographic recording materials HOECHST AKTIENGESELLSCHAFT (DE) 1986-01-02 — — EP claimed
US-4760006-A Photoconductive layer containing photoconductor, a binder and a sensitizing dyestuff on electroconductive support HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-26 — — US disclosed
US-4760006-A Photoconductive layer containing photoconductor, a binder and a sensitizing dyestuff on electroconductive support HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-26 — — US disclosed
US-4760006-A Photoconductive layer containing photoconductor, a binder and a sensitizing dyestuff on electroconductive support HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-26 — — US disclosed
EP-0166230-B1 2,3-BIS(DIALKYLAMINOPHENYL)QUINOXALINES AND THEIR USE IN ELECTROGRAPHIC RECORDING MATERIALS HOECHST AKTIENGESELLSCHAFT (DE) 1988-04-06 — — EP disclosed
EP-0166230-B1 2,3-BIS(DIALKYLAMINOPHENYL)QUINOXALINES AND THEIR USE IN ELECTROGRAPHIC RECORDING MATERIALS HOECHST AKTIENGESELLSCHAFT (DE) 1988-04-06 — — EP disclosed
EP-0166230-A1 2,3-Bis(dialkylaminophenyl)quinoxalines and their use in electrographic recording materials HOECHST AKTIENGESELLSCHAFT (DE) 1986-01-02 — — EP disclosed
EP-0166230-A1 2,3-Bis(dialkylaminophenyl)quinoxalines and their use in electrographic recording materials HOECHST AKTIENGESELLSCHAFT (DE) 1986-01-02 — — EP disclosed