Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 9/20 | 0.37 |
| ▸ | MAOA | P21397 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5186871 | 0.78 | DRD2 (0.46) | RAB9AMAPTKDM4E | |
| SCHEMBL2657694 | 0.77 | RAB9A (0.41) | RAB9AMAPTSMN1; SMN2KDM4EGAA | |
| SCHEMBL10698716 | 0.77 | MAPT (0.44) | RAB9AMAPTSMN1; SMN2KDM4EGAA | |
| SCHEMBL10697176 | 0.76 | MAPT (0.43) | RAB9AMAPTKDM4E | |
| SCHEMBL965277 | 0.76 | — | — | |
| SCHEMBL2374371 | 0.72 | RAB9A (0.53) | RAB9AMAPTSMN1; SMN2KDM4EGAA | |
| SCHEMBL1794807 | 0.72 | SMN1; SMN2 (0.53) | RAB9AMAPTSMN1; SMN2KDM4EGAA | |
| SCHEMBL1801634 | 0.71 | HSD17B10 (0.51) | RAB9AMAPTSMN1; SMN2KDM4EGAA | |
| SCHEMBL21275501 | 0.71 | RAB9A (0.43) | RAB9AMAPTSMN1; SMN2KDM4EGAA | |
| SCHEMBL10697144 | 0.70 | ALDH1A1 (0.47) | KDM4EGAAALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280873-A1 | Piperidines, medicines containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-09-07 | — | — | EP | disclosed |