Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 3/20 | 0.48 |
| ▸ | LAP3 | P28838 | 3/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10445568 | 0.87 | LTA4H (0.55) | SLC15A1LAP3LTA4HALDH1A1MAPK1 | |
| SCHEMBL10431947 | 0.84 | SLC15A1 (0.53) | SLC15A1LAP3LTA4HALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL6558239 | 0.80 | CYP1A2 (0.47) | SLC15A1LAP3LTA4HALDH1A1MAPK1 | |
| SCHEMBL10432041 | 0.79 | SLC15A1 (0.40) | SLC15A1ALDH1A1MAPK1L3MBTL1CYP1A2 | |
| SCHEMBL10432270 | 0.79 | ALPI (0.47) | SLC15A1LAP3LTA4HCTRB1ANPEP | |
| SCHEMBL7294329 | 0.79 | LTA4H (0.44) | SLC15A1LAP3LTA4HCTSLANPEP | |
| SCHEMBL10445629 | 0.78 | MDM2 (0.49) | SLC15A1LAP3LTA4HCYP1A2CTRB1 | |
| SCHEMBL10445400 | 0.77 | LTA4H (0.48) | LAP3LTA4HALDH1A1ANPEP | |
| Hydrochloric Acid SCHEMBL6558386 | 0.77 | HRH4 (0.45) | SLC15A1LAP3LTA4HALDH1A1MAPK1 | |
| SCHEMBL9724712 | 0.76 | CSNK1E (0.46) | SLC15A1LAP3LTA4HALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0275101-A2 | Novel peptidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-07-20 | — | — | EP | disclosed |