Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | LAP3 | P28838 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10445568 | 0.85 | LTA4H (0.55) | TDP1L3MBTL1ALDH1A1MAPK1LTA4H | |
| SCHEMBL7294329 | 0.81 | LTA4H (0.44) | TDP1LTA4HLAP3POLBSLC15A1 | |
| SCHEMBL8749526 | 0.81 | LAP3 (0.60) | CSNK1ERENTSHRTDP1L3MBTL1 | |
| SCHEMBL14119782 | 0.81 | LAP3 (0.60) | CSNK1ERENTSHRTDP1L3MBTL1 | |
| SCHEMBL10432270 | 0.79 | ALPI (0.47) | CSNK1ELTA4HLAP3SLC15A1ANPEP | |
| SCHEMBL10432328 | 0.77 | RAB9A (0.49) | L3MBTL1ALDH1A1MAPK1LMNANPC1 | |
| SCHEMBL216480 | 0.76 | ALPI (0.54) | CSNK1ETSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL2734875 | 0.76 | ALPI (0.54) | CSNK1ETSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL10445629 | 0.76 | MDM2 (0.49) | CSNK1ELTA4HLAP3SLC15A1ANPEP | |
| SCHEMBL10697296 | 0.76 | SLC15A1 (0.48) | L3MBTL1ALDH1A1CYP3A4MAPK1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114927-A | Hypotensive agents and inhibiting renin | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-05-19 | — | — | US | disclosed |