SCHEMBL4298981

SCHEMBL4298981

CCCOC(Cc1ccccc1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ SRR Q9GZT4 2/20 0.59
▸ PPARG P37231 18/20 0.56
▸ PPARA Q07869 17/20 0.56
▸ PPARD Q03181 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8072578 0.90 PPARA (0.59) SRRPPARGPPARAPPARD
SCHEMBL1165783 0.89 PPARA (0.54) SRRPPARGPPARAPPARD
SCHEMBL1932308 0.88 SRR (0.61) SRRPPARGPPARA
SCHEMBL5607130 0.87 PPARA (0.75) PPARGPPARAPPARD
SCHEMBL10697327 0.87 PPARA (0.53) SRRPPARGPPARAPPARD
SCHEMBL8084774 0.87 PPARA (0.53) SRRPPARGPPARAPPARD
SCHEMBL4041857 0.87 PPARA (0.53) SRRPPARGPPARAPPARD
SCHEMBL543191 0.87 PPARA (0.56) SRRPPARGPPARAPPARD
SCHEMBL7630188 0.87 PPARA (0.56) SRRPPARGPPARAPPARD
SCHEMBL4993002 0.86 PPARA (0.69) SRRPPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090088438-A1 NEW TYROSINE DERIVATIVES AS PPARy MODULATORS LABORATORIOS SALVAT, S.A. (ES) 2009-04-02 — — US disclosed
US-7423172-B2 Tyrosine derivatives as PPAR-γ-modulators LABORATORIOS SALVAT, S.A. (ES) 2008-09-09 — — US disclosed
US-20070276043-A1 Tyrosine Derivatives As Ppar-Gamma-Modulators LABORATORIES SALVAT, S.A. (ES) 2007-11-29 — — US disclosed
EP-0758013-B1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL CO LTD (JP) 2000-10-11 — — EP disclosed
US-5855971-A Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film NIPPON OIL COMPANY, LIMITED (JP) 1999-01-05 — — US disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090088438-A1 NEW TYROSINE DERIVATIVES AS PPARy MODULATORS PPARG, PPARD, TYRO3 SRR 983/4885PPARG 1/4885PPARA 4/4885
US-20070276043-A1 Tyrosine Derivatives As Ppar-Gamma-Modulators PPARG, PPARD, PPARA SRR 950/4885PPARG 1/4885PPARA 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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