Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 2/20 | 0.39 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093557 | 0.82 | KDM4E (0.52) | KDM4EHSD17B10HTTGAAMAPT | |
| SCHEMBL812108 | 0.82 | MAPK1 (0.57) | KDM4EHSD17B10HTTGAAMAPT | |
| SCHEMBL11477096 | 0.81 | KDM4E (0.40) | KDM4EHSD17B10HTTGAAMAPT | |
| SCHEMBL6331609 | 0.79 | CA1 (0.52) | KDM4EHSD17B10MAPTTP53ALDH1A1 | |
| SCHEMBL10808312 | 0.76 | MAPK1 (0.62) | KDM4EHSD17B10HTTGAAMAPT | |
| SCHEMBL2047863 | 0.76 | KDM4E (0.62) | KDM4EHSD17B10HTTGAAMAPT | |
| SCHEMBL10697403 | 0.75 | MAPK1 (0.45) | KDM4EHSD17B10GAAMAPTALDH1A1 | |
| SCHEMBL24436699 | 0.74 | KDM4E (0.45) | KDM4EHSD17B10HTTGAAMAPT | |
| SCHEMBL3137273 | 0.74 | PREP (0.50) | KDM4EHSD17B10HTTGAAMAPT | |
| SCHEMBL10935928 | 0.73 | ELANE (0.51) | KDM4EHSD17B10HTTGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0265185-A2 | Cephalosporins, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-04-27 | — | — | EP | disclosed |