Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6197525 | 0.84 | MAOB (0.45) | MAPK1PTGS2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL744605 | 0.83 | PTGS2 (0.53) | MAPK1PTGS2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8766243 | 0.82 | KDM4E (0.55) | MAPK1PTGS2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL5566305 | 0.82 | ACHE (0.56) | MAPK1PTGS2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL812108 | 0.82 | MAPK1 (0.57) | MAPK1PTGS2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL4229681 | 0.79 | KDM4E (0.57) | MAPK1PTGS2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL1458762 | 0.79 | HSD17B10 (0.56) | MAPK1PTGS2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2878372 | 0.76 | KDM4E (0.57) | MAPK1PTGS2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL6198034 | 0.76 | PTPN1 (0.54) | MAPK1PTGS2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL10697401 | 0.75 | KDM4E (0.42) | MAPK1KDM4EHSD17B10ALDH1A1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0265185-A2 | Cephalosporins, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-04-27 | — | — | EP | disclosed |