Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 5/20 | 0.33 |
| ▸ | HTR2B | P41595 | 4/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697433 | 0.84 | IDO1 (0.36) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL9876363 | 0.77 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL9876395 | 0.75 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3KDM1AMAOB | |
| SCHEMBL9876253 | 0.72 | EPHX2 (0.33) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL9876112 | 0.65 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL9876114 | 0.65 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL10178470 | 0.65 | SLC6A2 (0.47) | SLC6A4SLC6A2SLC6A3MAOBHTR2C | |
| SCHEMBL10177764 | 0.62 | HTR2C (0.53) | SLC6A4SLC6A2SLC6A3KDM1AALDH1A1 | |
| SCHEMBL16234301 | 0.62 | HTR2C (0.53) | SLC6A4SLC6A2SLC6A3KDM1AALDH1A1 | |
| SCHEMBL10177774 | 0.62 | HTR2C (0.53) | SLC6A4SLC6A2SLC6A3KDM1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254078-A1 | Pyran derivatives | BASF Aktiengesellschaft (DE) | 1988-01-27 | — | — | EP | disclosed |