Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876112 | 1.00 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3EPHX2KDM1A | |
| SCHEMBL4512850 | 0.75 | ALDH1A1 (0.33) | SLC6A2SLC6A3KDM1AMAOAMAOB | |
| SCHEMBL9361111 | 0.72 | TSHR (0.32) | KDM1A | |
| SCHEMBL11371142 | 0.72 | KDM4E (0.34) | TDP1KMT2A | |
| SCHEMBL6854408 | 0.70 | ALDH1A1 (0.38) | TDP1MEN1KMT2A | |
| SCHEMBL9876363 | 0.65 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3EPHX2KDM1A | |
| SCHEMBL10697410 | 0.65 | SLC6A4 (0.40) | SLC6A4SLC6A2SLC6A3EPHX2KDM1A | |
| SCHEMBL3441836 | 0.65 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3MAOAMAOB | |
| SCHEMBL11599949 | 0.63 | HTR2C (0.33) | SLC6A2SLC6A3KDM1AMAOAMAOB | |
| SCHEMBL10964843 | 0.60 | SLC6A3 (0.48) | SLC6A4SLC6A2SLC6A3EPHX2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254078-B1 | PYRAN DERIVATIVES | BASF Aktiengesellschaft (DE) | 1991-02-06 | — | — | EP | disclosed |
| EP-0254078-A1 | Pyran derivatives | BASF Aktiengesellschaft (DE) | 1988-01-27 | — | — | EP | disclosed |