Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.39 |
| ▸ | KDM1A | O60341 | 5/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876363 | 0.75 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3KDM1AMAOA | |
| SCHEMBL10697410 | 0.75 | SLC6A4 (0.40) | SLC6A4SLC6A2SLC6A3KDM1AMAOA | |
| SCHEMBL10697433 | 0.72 | IDO1 (0.36) | SLC6A4SLC6A2SLC6A3KDM1AMAOA | |
| SCHEMBL9876253 | 0.71 | EPHX2 (0.33) | SLC6A4SLC6A2SLC6A3FFAR4EPHX2 | |
| SCHEMBL11818288 | 0.66 | MAOA (0.47) | SLC6A4MAOAMAOBPPARGPPARA | |
| SCHEMBL9876114 | 0.63 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3KDM1AMAOA | |
| SCHEMBL9876112 | 0.63 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3KDM1AMAOA | |
| SCHEMBL24256662 | 0.63 | SLC5A1 (0.43) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL6917165 | 0.61 | HRH1 (0.47) | SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL21550571 | 0.61 | HTR2A (0.45) | KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254078-B1 | PYRAN DERIVATIVES | BASF Aktiengesellschaft (DE) | 1991-02-06 | — | — | EP | disclosed |
| EP-0254078-A1 | Pyran derivatives | BASF Aktiengesellschaft (DE) | 1988-01-27 | — | — | EP | disclosed |