Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876644 | 0.81 | GRIN2B (0.35) | EPHX2SLC6A4SLC6A2SLC6A3GRIN2B | |
| SCHEMBL9876363 | 0.75 | SLC6A4 (0.39) | EPHX2SLC6A4SLC6A2SLC6A3GRIN2B | |
| SCHEMBL10697433 | 0.74 | IDO1 (0.36) | EPHX2SLC6A4SLC6A2SLC6A3GRIN2B | |
| SCHEMBL10697410 | 0.72 | SLC6A4 (0.40) | EPHX2SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL9876395 | 0.71 | SLC6A4 (0.39) | EPHX2SLC6A4SLC6A2SLC6A3FFAR4 | |
| SCHEMBL9876114 | 0.61 | SLC6A4 (0.38) | EPHX2SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL9876112 | 0.61 | SLC6A4 (0.38) | EPHX2SLC6A4SLC6A2SLC6A3MEN1 | |
| SCHEMBL3441836 | 0.58 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL19950989 | 0.56 | MEN1 (0.59) | GRIN2BMEN1KMT2ASLC18A3SIGMAR1 | |
| SCHEMBL14232386 | 0.55 | SLC18A3 (0.52) | SLC18A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254078-B1 | PYRAN DERIVATIVES | BASF Aktiengesellschaft (DE) | 1991-02-06 | — | — | EP | disclosed |
| EP-0254078-A1 | Pyran derivatives | BASF Aktiengesellschaft (DE) | 1988-01-27 | — | — | EP | disclosed |