SCHEMBL10697590

SCHEMBL10697590

CCOc1ccc(N=C=O)c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.42
TRPA1 O75762 1/20 0.42
NQO1 P15559 1/20 0.42
ALDH1A1 P00352 7/20 0.41
HPGD P15428 4/20 0.41
KDM4E B2RXH2 4/20 0.41
TDP1 Q9NUW8 3/20 0.40
MAPT P10636 3/20 0.39
HSD17B10 Q99714 3/20 0.39
ESR2 Q92731 1/20 0.39
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
TSHR P16473 2/20 0.38
LMNA P02545 2/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CYP1A2 P05177 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA5A P35218 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8564350 0.88 CYP3A4 (0.43) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL10341831 0.88 CYP3A4 (0.43) CYP3A4TRPA1ALDH1A1HPGDKDM4E
SCHEMBL10341987 0.87 PDIA6 (0.47) CYP3A4TRPA1ALDH1A1HPGDKDM4E
SCHEMBL27721536 0.82 NQO1 (0.41) CYP3A4NQO1ALDH1A1HPGDKDM4E
SCHEMBL9918950 0.81 ALDH1A1 (0.46) CYP3A4TRPA1ALDH1A1HPGDKDM4E
SCHEMBL10341851 0.81 CYP3A4 (0.49) CYP3A4TRPA1ALDH1A1HPGDKDM4E
SCHEMBL8567728 0.81 CYP3A4 (0.49) CYP3A4TRPA1ALDH1A1HPGDTDP1
SCHEMBL12329846 0.81 MAPT (0.47) CYP3A4NQO1ALDH1A1HPGDKDM4E
SCHEMBL162798 0.81 CYP3A4 (0.51) CYP3A4TRPA1ALDH1A1HPGDKDM4E
SCHEMBL10341870 0.80 CYP3A4 (0.47) CYP3A4TRPA1ALDH1A1HPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0270906-A1 Diisocyanates and diisocyanate mixtures, process for their preparation and their use in the preparation of polyurethane plastics BAYER AG (DE) 1988-06-15 EP disclosed