Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MPI | P34949 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26093677 | 0.79 | KDM4E (0.55) | KDM4EALDH1A1GAAMPIGFER | |
| SCHEMBL30387478 | 0.79 | KDM4E (0.55) | KDM4EALDH1A1GAAMPIGFER | |
| SCHEMBL10697621 | 0.76 | KDM4E (0.59) | KDM4EALDH1A1GAAMPIGFER | |
| SCHEMBL1613151 | 0.76 | ALDH1A1 (0.47) | KDM4EALDH1A1GAAMPIGFER | |
| SCHEMBL24088760 | 0.74 | NPC1 (0.45) | KDM4EMAPK1MAPTMEN1KMT2A | |
| SCHEMBL13115362 | 0.74 | NPC1 (0.42) | KDM4EALDH1A1GAAHPGD | |
| SCHEMBL13803942 | 0.74 | HTT (0.42) | KDM4EALDH1A1GAAMPIGFER | |
| SCHEMBL12374645 | 0.74 | MAPT (0.51) | KDM4EALDH1A1MAPK1HSD17B10MAPT | |
| SCHEMBL29008462 | 0.74 | ALDH1A1 (0.50) | KDM4EALDH1A1GAAMPIHSD17B10 | |
| SCHEMBL535052 | 0.73 | PDE5A (0.44) | KDM4EALDH1A1GAAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116194537-A | Combination therapy with adenosine receptor antagonists | 泰昂治疗公司 | 2023-05-30 | — | — | CN | disclosed |