Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | PKM | P14618 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | ABL1 | P00519 | 3/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL206539 | 0.87 | SMN1; SMN2 (0.77) | ALDH1A1SMN1; SMN2KDM4ETDP1MAPT | |
| SCHEMBL16607311 | 0.87 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2KDM4ETDP1MAPT | |
| SCHEMBL2020280 | 0.85 | ABL1 (0.73) | ALDH1A1SMN1; SMN2KDM4EMAPTMEN1 | |
| SCHEMBL10699534 | 0.85 | ABL1 (0.73) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL25287793 | 0.83 | LMNA (0.90) | ALDH1A1SMN1; SMN2KDM4ETDP1MAPT | |
| SCHEMBL30058875 | 0.82 | ABL1 (0.72) | ALDH1A1SMN1; SMN2KDM4ETDP1MAPT | |
| SCHEMBL11790758 | 0.82 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2KDM4ETDP1MAPT | |
| SCHEMBL11783863 | 0.82 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2KDM4ETDP1MAPT | |
| SCHEMBL8277912 | 0.82 | MAPK1 (0.68) | ALDH1A1SMN1; SMN2KDM4ETDP1MAPT | |
| SCHEMBL7679868 | 0.82 | MAPK1 (0.82) | ALDH1A1SMN1; SMN2TDP1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280873-A1 | Piperidines, medicines containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-09-07 | — | — | EP | disclosed |