Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31678725 | 0.89 | SLC6A2 (0.42) | KIF11SLC6A2NOTUMTSHRHTR1D | |
| Hydrochloric Acid SCHEMBL27699821 | 0.78 | BACE1 (0.44) | KIF11NOTUMCYP1A2TNKSTNKS2 | |
| Formaldehyde SCHEMBL27609576 | 0.77 | TSHR (0.40) | KIF11SLC6A2NOTUMTSHRHTR1D | |
| SCHEMBL728223 | 0.77 | NPC1 (0.39) | LMNANPC1RAB9ACYP1A2MEN1 | |
| SCHEMBL6319811 | 0.73 | ALDH1A1 (0.60) | NPC1MEN1ALDH1A1MAPK1KMT2A | |
| SCHEMBL6287799 | 0.72 | TSHR (0.43) | KIF11SLC6A2NOTUMTSHRHTR1D | |
| SCHEMBL24923799 | 0.72 | ALDH1A1 (0.44) | NOTUMTSHRNPC1RAB9ACYP1A2 | |
| SCHEMBL8649025 | 0.72 | PTGS2 (0.42) | NISCHNPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL15258336 | 0.71 | HSD17B1 (0.48) | KIF11LMNARAB9AMAPK1KMT2A | |
| SCHEMBL10699917 | 0.71 | BRD4 (0.41) | KIF11SLC6A2NOTUMTSHRHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259977-A2 | Tertiary amine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-16 | — | — | EP | disclosed |