SCHEMBL10697714

SCHEMBL10697714

C=CCON=C1COC2C(O)COC12

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.40
CHRM1 P11229 1/20 0.40
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10697186 0.78 ALDH1A1 (0.45) CHRM2CHRM1ALDH1A1
SCHEMBL10552467 0.71 THRB (0.41)
SCHEMBL372212 0.67 THRB (0.44)
SCHEMBL12966695 0.67 THRB (0.44)
SCHEMBL8293189 0.67 THRB (0.44)
Isosorbide SCHEMBL618288 0.66 THRB (0.54) ALDH1A1
SCHEMBL10747010 0.62 THRB (0.31)
SCHEMBL10745265 0.62 THRB (0.31)
SCHEMBL22371893 0.61 THRB (0.46) ALDH1A1
SCHEMBL17864238 0.61 THRB (0.46) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0284752-A1 Oxime ethers of 2,6-dioxabicyclo[3.3.0]octanones Heinrich Mack Nachf. (DE) 1988-10-05 EP disclosed