Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10745265 | 0.77 | THRB (0.31) | THRBLMNA | |
| SCHEMBL15218988 | 0.75 | THRB (0.44) | THRBLMNAMAPT | |
| SCHEMBL196060 | 0.75 | THRB (0.44) | THRBLMNAMAPT | |
| SCHEMBL10048336 | 0.75 | THRB (0.44) | THRBLMNAMAPT | |
| SCHEMBL10016808 | 0.75 | THRB (0.44) | THRBLMNAMAPT | |
| SCHEMBL1735065 | 0.75 | THRB (0.44) | THRBLMNAMAPT | |
| SCHEMBL10747010 | 0.73 | THRB (0.31) | THRBLMNA | |
| Isosorbide SCHEMBL699485 | 0.72 | THRB (0.52) | THRBLMNAMAPT | |
| SCHEMBL10697714 | 0.71 | CHRM2 (0.40) | — | |
| SCHEMBL8293189 | 0.71 | THRB (0.44) | THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4883796-A | Oxime ethers of 2,6-dioxabicyclo(3.3.0)octanones, and compositions and methods for treatment of a cardiac disease or circulatory with them | HEINRICH MACK NACHF. (DE) | 1989-11-28 | — | — | US | disclosed |