Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27603483 | 0.87 | KDM4E (0.47) | KDM4EGLAMAPTPOLBGAA | |
| SCHEMBL38661512 | 0.86 | KDM4E (0.46) | KDM4EGLAMAPTPOLBGAA | |
| SCHEMBL3180180 | 0.80 | TDP1 (0.40) | POLBHTTPTGS2PTGS1HPGD | |
| SCHEMBL8324702 | 0.80 | PTGS1 (0.57) | KDM4EMAPTPOLBGAAHTT | |
| SCHEMBL3984863 | 0.77 | KDM4E (0.42) | KDM4EGLAMAPTPOLBGAA | |
| SCHEMBL283021 | 0.77 | GABRA1 (0.46) | KDM4EGLAMAPTPOLBGAA | |
| SCHEMBL8157598 | 0.76 | GRM1 (0.41) | HTTPTGS2PTGS1LMNAPPARA | |
| SCHEMBL1678995 | 0.76 | GRM1 (0.41) | HTTPTGS2PTGS1LMNAPPARA | |
| SCHEMBL16293581 | 0.76 | PTGS1 (0.60) | KDM4EMAPTPOLBPTGS2PTGS1 | |
| SCHEMBL16293535 | 0.76 | PTGS1 (0.60) | KDM4EMAPTPOLBPTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255178-A2 | Process for preparing hetero aryl and aryl alkanoic acids | Nobel Chemicals AB (SE) | 1988-02-03 | — | — | EP | disclosed |