Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10700743 | 0.90 | MEN1 (0.33) | MEN1KMT2ARAB9AALDH1A1KDM4E | |
| SCHEMBL10697223 | 0.87 | MEN1 (0.38) | AURKAAURKBMEN1KMT2ARAB9A | |
| SCHEMBL10699175 | 0.87 | AURKA (0.38) | AURKAAURKBKMT2ACHEK1SRC | |
| SCHEMBL10697092 | 0.86 | CREBBP (0.36) | CNR1GPR55MEN1KMT2ARAB9A | |
| SCHEMBL10698519 | 0.84 | CNR1 (0.41) | CNR1GPR55AURKAAURKBMEN1 | |
| SCHEMBL10699079 | 0.81 | HTT (0.39) | AURKAAURKBMEN1KMT2ARAB9A | |
| SCHEMBL10697525 | 0.79 | MEN1 (0.36) | MEN1KMT2ARAB9AALDH1A1KDM4E | |
| SCHEMBL10698674 | 0.78 | KDM4E (0.34) | ALDH1A1CASP1CASP7KDM4EHSD17B10 | |
| SCHEMBL10700985 | 0.78 | KMT2A (0.36) | MEN1KMT2ARAB9AALDH1A1CASP1 | |
| SCHEMBL10699610 | 0.77 | MEN1 (0.36) | MEN1KMT2ARAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |