Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10699610 | 0.90 | MEN1 (0.36) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL10697223 | 0.90 | MEN1 (0.38) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL10700743 | 0.89 | MEN1 (0.33) | MEN1KMT2AALDH1A1KDM4ERAB9A | |
| SCHEMBL10698674 | 0.88 | KDM4E (0.34) | ALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL10700232 | 0.85 | TNKS2 (0.43) | MEN1KMT2AALDH1A1KDM4ECA1 | |
| SCHEMBL10698445 | 0.80 | MEN1 (0.36) | MEN1KMT2AALDH1A1KDM4ECA1 | |
| SCHEMBL10698933 | 0.80 | KMT2A (0.36) | MEN1KMT2AALDH1A1KDM4ECA1 | |
| SCHEMBL10697809 | 0.79 | CNR1 (0.39) | MEN1KMT2AALDH1A1KDM4ERAB9A | |
| SCHEMBL10698676 | 0.78 | KDM4E (0.35) | ALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL10700189 | 0.78 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |