Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM6B | O15054 | 3/20 | 0.49 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ASPH | Q12797 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809308 | 0.98 | ALDH1A1 (0.61) | ALDH1A1HSD17B10HPGDKDM4CKDM4E | |
| Hydrochloric Acid SCHEMBL516167 | 0.93 | ALDH1A1 (0.63) | ALDH1A1HSD17B10HPGDKDM4CKDM4E | |
| SCHEMBL9809381 | 0.88 | ALDH1A1 (0.69) | ALDH1A1HSD17B10HPGDKDM4CKDM4E | |
| SCHEMBL8689214 | 0.88 | ALDH1A1 (0.79) | ALDH1A1HSD17B10HPGDKDM4CKDM4E | |
| SCHEMBL8847289 | 0.83 | ALDH1A1 (0.63) | ALDH1A1HSD17B10HPGDKDM4CKDM4E | |
| SCHEMBL5510920 | 0.83 | ALDH1A1 (0.78) | ALDH1A1HSD17B10HPGDKDM4CKDM4E | |
| SCHEMBL466141 | 0.83 | PLK1 (0.63) | ALDH1A1HSD17B10HPGDKDM4CKDM4E | |
| SCHEMBL1665592 | 0.83 | ALDH1A1 (0.67) | ALDH1A1HSD17B10HPGDKDM4CKDM4E | |
| SCHEMBL3475665 | 0.82 | PLK1 (0.66) | ALDH1A1HSD17B10HPGDKDM4CKDM4E | |
| SCHEMBL5272720 | 0.82 | PLK1 (0.66) | ALDH1A1HSD17B10HPGDKDM4CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284413-A2 | Derivative of a fibrinolytic enzyme | BEECHAM GROUP PLC (GB) | 1988-09-28 | — | — | EP | disclosed |