SCHEMBL1665592

SCHEMBL1665592

O=C(O)c1ccccc1NCCCO

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.67
HSD17B10 Q99714 4/20 0.67
HPGD P15428 4/20 0.67
KDM4E B2RXH2 4/20 0.56
AGTR1 P30556 1/20 0.56
RAB9A P51151 1/20 0.56
HTT P42858 1/20 0.55
GLA P06280 1/20 0.54
POLB P06746 1/20 0.53
CTDSP1 Q9GZU7 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
KDM4C Q9H3R0 4/20 0.49
KDM6B O15054 3/20 0.49
FABP4 P15090 2/20 0.49
FABP3 P05413 1/20 0.49
FABP5 Q01469 1/20 0.49
PLK1 P53350 1/20 0.48
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9279236 0.89 ALDH1A1 (0.71) ALDH1A1HSD17B10HPGDKDM4EAGTR1
SCHEMBL8689214 0.87 ALDH1A1 (0.79) ALDH1A1HSD17B10HPGDKDM4EAGTR1
SCHEMBL27851818 0.84 KDM4E (0.53) ALDH1A1HSD17B10HPGDKDM4EAGTR1
SCHEMBL5515007 0.84 ALDH1A1 (0.81) ALDH1A1HSD17B10HPGDKDM4EAGTR1
SCHEMBL993102 0.84 HPGD (0.65) ALDH1A1HSD17B10HPGDKDM4EAGTR1
SCHEMBL8847289 0.83 ALDH1A1 (0.63) ALDH1A1HSD17B10HPGDKDM4EAGTR1
SCHEMBL5510920 0.83 ALDH1A1 (0.78) ALDH1A1HSD17B10HPGDKDM4EAGTR1
SCHEMBL466141 0.83 PLK1 (0.63) ALDH1A1HSD17B10HPGDKDM4EAGTR1
SCHEMBL10697917 0.83 ALDH1A1 (0.63) ALDH1A1HSD17B10HPGDKDM4EAGTR1
SCHEMBL4897624 0.83 KDM6B (0.69) ALDH1A1HSD17B10HPGDKDM4EAGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0552289-A4 PREVENTION OR TREATMENT OF SUNBURN USING THE S(+) ISOMER OF KETOPROFEN 1993-08-11 EP claimed
EP-0552289-A1 PREVENTION OR TREATMENT OF SUNBURN USING THE S(+) ISOMER OF KETOPROFEN MILES INC. (US) 1993-07-28 EP claimed
WO-1992005769-A1 PREVENTION OR TREATMENT OF SUNBURN USING THE S(+) ISOMER OF KETOPROFEN MILES, INC. (US) 1992-04-16 WO claimed
US-5093107-A Ultraviolet absorber, hydrophobic silicone, fatty acid wax in anhydrous carrier NEUTROGENA CORPORATION (US) 1992-03-03 US claimed
WO-1991017740-A1 PREVENTION OR TREATMENT OF SUNBURN USING THE S(+) ISOMER OF FLURBIPROFEN ANALGESIC ASSOCIATES (US) 1991-11-28 WO claimed
EP-2488486-B1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES LIGAND PHARM INC (US) 2019-08-14 EP disclosed
US-10351322-B2 Aerator device and UV protecting cover member therefor AQUACONSULT ANLAGENBAU GMBH (AT) 2019-07-16 US disclosed
US-9622991-B2 Hematopoietic growth factor mimetic small molecule compounds and their uses LIGAND PHARMACEUTICALS INC. (US) 2017-04-18 US disclosed
US-9578878-B2 Antimicrobial efficacy of an oregano oil and caprylic acid blend KEMIN INDUSTRIES, INC. (US) 2017-02-28 US disclosed
US-20160199793-A1 AERATOR DEVICE AND UV PROTECTING COVER MEMBER THEREFOR AQUACONSULT ANLAGENBAU GMBH (AT) 2016-07-14 US disclosed
US-9144557-B2 Hematopoietic growth factor mimetic small molecule compounds and their uses LIGAND PHARMACEUTICALS INC. (US) 2015-09-29 US disclosed
US-20150252043-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2015-09-10 US disclosed
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles BIODERM RESEARCH (US) 2008-10-16 US disclosed
CN-100351296-C Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM & HAAS (US) 2007-11-28 CN disclosed
US-20070166339-A1 Skin Whitening Methods and Compositions Based on Zeolite - Active Oxygen Donor Complexes BIODERM RESEARCH (US) 2007-07-19 US disclosed
CN-1765961-A Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM & HAAS (US) 2006-05-03 CN disclosed
EP-1401968-A1 AQUEOUS COATING COMPOSITION CONTAINING UV RADIATION ABSORBING AGENTS RHODIA CHIMIE (FR) 2004-03-31 EP disclosed
WO-2002100958-A1 AQUEOUS COATING COMPOSITION CONTAINING UV RADIATION ABSORBING AGENTS RHODIA CHIMIE (FR) 2002-12-19 WO disclosed
EP-0901512-A1 DETERGENT COMPOSITION UNILEVER PLC (GB) 1999-03-17 EP disclosed
WO-1997044422-A1 DETERGENT COMPOSITION UNILEVER PLC (GB) 1997-11-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150252043-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES MPL, CSF3R, HGF ALDH1A1 2736/4885HSD17B10 4495/4885HPGD 1328/4885
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles PROC, COL1A1, CUTA ALDH1A1 35/4885HSD17B10 183/4885HPGD 725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.